SIMPLE METHOD OF BIOLOGICALLY EVALUATING NATURAL A

专利名称：SIMPLE METHOD OF BIOLOGICALLY

EVALUATING NATURAL AND ARTIFICIALCHEMICALS BY USING DNA INJURY INDEXAND APPARATUS THEREFOR

发明人：TAKAKI, Atsushi申请号：EP01912426.2申请日：20010316公开号：EP1267162A1公开日：20021218

摘要：A biological evaluation method for rational and simply evaluating biologicalharmfulness or usefulness of a great number of natural and artificial chemicals, foods,etc. This method comprises adding a known amount of 2'-deoxyguanosine (dG) to asolution containing a test substance (drug, pesticide, functional food, etc.), optionallyapplying UV light and/or adding active oxygen generator, then quantifying 8-hydroxy-2'-deoxyguanosine (8OHdG) in the solution, and evaluating the toxicity or usefulness of thetest substance according to the 8OhdG content (a higher 8OhdG content indicates ahigher harmfulness of the test substance while a lower 8OhdG content indicates a lowerharmfulness or an usefulness thereof). The invention also provide an apparatus foradvantageously performing said biological evaluation method and an antioxidantpreservative solution to be used in this apparatus.

申请人：Ecological Technology Research, Ltd.,Kyushu Tlo Company, Limited

地址：1124-1, Ooaza kamishirohzu Kasuga-shi, Fukuoka 816-0844 JP,10-1, Hakozaki 6-chome, Higashi-ku Fukuoka-shi, Fukuoka 812-8581 JP

国籍：JP,JP

代理机构：Schwabe - Sandmair - Marx

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