3-Hydroxy-3-methylglutaryl-CoA reductase polynucle

专利名称：3-Hydroxy-3-methylglutaryl-CoA reductase

polynucleotides in isoprenoid production

发明人：Tatsuo Hoshino,Kazuyuki Ojima,Yutaka

Setoguchi

申请号：US09306595申请日：19990506公开号：US06284506B1公开日：20010904

专利附图：

摘要：The present invention relates to an isolated DNA sequence encoding an enzymein the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl

pyrophosphate (i.e., HMG-CoA synthase, HMG-CoA reductase, mevalonate kinase,mevalonate pyrophosphate decarboxylase, and FPP synthase). Vectors and plasmidsincluding such DNA, are also set forth. The invention also includes host cells transformedby such DNAs, or vectors or plasmids containing such DNAs. A process for the productionof isoprenoids and carotenoids using such transformed host cells is also provided.

申请人：ROCHE VITAMINS INC.

代理机构：Bryan Cave LLP

代理人：Mark E. Waddell,Stephen M. Haracz

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